- Once daily injection
- Clinically Proven
- Licensed for weight loss
- Support from our Medical Team
Saxenda is an injectable weight loss aid which is often prescribed when other weight loss efforts have been ineffective. It is only available on prescription in the UK.
Each pen is prefilled with 6mg/ml liraglutide - the same active ingredient found in other weight loss injection pens such as the Skinny Jab.
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Saxenda is a once-daily injection that you administer to yourself to aid weight loss. It contains the active ingredient Liraglutide, which is very similar to a naturally occurring hormone in your body called GLP-1. It works by making you feel less hungry, slowing down the emptying of your stomach and making you feel 'fuller' for longer.
How does Saxenda work?
Saxenda (liraglutide 6mg/ml) is a self-injectable weight loss treatment. It contains the active ingredient liraglutide which is very similar to a naturally occurring hormone in your body called GLP-1.
After a meal GLP-1 is naturally released from your intestines to help regulate your blood sugar levels and reduce the amount of glucagon in your body. Glucagon is a naturally occurring hormone which works by inhibiting the action of insulin. As a result, it makes you feel less hungry, slows down the emptying of your stomach and makes you feel 'fuller' for longer.
How do I take Saxenda?
Saxenda comes in a 3ml pre-filled injection pen. The pen contains a clear and colourless or almost colourless solution. All pens are supplied with the right quantity of needles you require for injecting. You will need to store your Saxenda pre-filled pen in a refrigerator (2°C to 8°C) before your first use. Once you start using the pen, you can keep it for 1 month either at room temperature (2 to 30°C) or in a refrigerator (2°C to 8°C). Do not freeze.
When you take Saxenda you need to gradually increase your dose in 0.6mg intervals, until you reach what is called the maintenance dose at 3mg daily. This is the dose at which you will continue to take Saxenda. You increase your dose as follows:
- Week 1 – 0.6mg as a once-daily injection
- Week 2 – 1.2mg as a once-daily injection
- Week 3 – 1.8mg as a once-daily injection
- Week 4 – 2.4mg as a once-daily injection
- Week 5 onwards – maintenance dose of 3.0mg as a once-daily injection
Increasing the dose slowly over time should minimise any unwanted side effects, such as nausea, vomiting and diarrhoea. As you increase your dose, if you find that you cannot tolerate your side effects, you should stay on the same dose for 2 continuous weeks. If after 2 weeks your side effects are still not tolerable, you should consider stopping treatment.
The maximum recommended daily dosage of liraglutide is 3.0mg. Try to take it at the same time each day, picking a time that works for you, with or without food or drink.
You must continue with your new diet and exercise regime while you are taking Saxenda.
Always use Saxenda exactly how your prescriber has told you. Check with your doctor, pharmacist or nurse if you are unsure.
When you first start Saxenda, a single pen will last 17 days and the first full pack of five pens will last six weeks. Once you have achieved the maintenance dose, a pack of five pens will last 30 days.
Where do I inject Saxenda?
- Saxenda is administered once daily.
- Inject your dose of Saxenda under the skin (subcutaneous injection) in your stomach area (abdomen), upper leg (thigh), or upper arm. It is also recommended that you alternate the site at which the injection is made.
Do not inject into a vein or muscle.
- Pinch the skin and push the needle all the way into the skin at a 90º angle.
- Let go of the pinched skin. Inject the Saxenda and leave the syringe in place while you count slowly to 6 to make sure the full dose is delivered.
- If the disposable needle found at the tip of one of your Saxenda pens bends out of shape whilst you are trying to use the pen, you should discard the needle and use a new one.
- Never share your Saxenda pen or needles with another person. You may give an infection to them, or get an infection from them.
When do I take Saxenda?
Saxenda can be taken at any time of the day, with or without food and drink, but you must stick to taking it at the same time each day such as at breakfast or bedtime. Choose a time of the day that works best for you.
What are the possible side effects of Saxenda?
As with all medication, Saxenda can be associated with unwanted side effects. Although usually mild, some can be more severe, which may result in your treatment being stopped. You should always read the patient information leaflet fully before you begin treatment.
When you first start your treatment, you may experience some stomach upset, such as vomiting or diarrhoea, and may also lose some bodily fluids. Therefore, it is important to drink plenty of fluids to keep yourself hydrated. Most mild side effects will settle once your body gets used to the new medication. However, if any side effect persists, stop the treatment and talk to a doctor.
Sometimes side effects of Saxenda can be very serious, such as severe allergic reactions. If you get any symptoms, such as problems breathing, swelling of your face or throat, or a fast heartbeat, you must get medical help immediately.
Rarely there have been cases reported of inflammation of the pancreas (pancreatitis). Pancreatitis is a serious, potentially life-threatening, medical condition. If you experience any of the following side effects stop taking Saxenda immediately and get medical help: severe and persistent pain in the abdomen (stomach area) which might reach through to your back with nausea or vomiting.
Side effects can include, but are not limited to:
Very common side effects (may affect more than 1 user in 10 users)
Nausea vomiting (settles after your body adjusts to treatment)
Diarrhoea or constipation (settles after your body adjusts to treatment)
Common side effects (may affect up to 1 to 10 users)
Low blood sugar. The warning signs of low blood sugar may come on suddenly and can include: cold sweat, cool pale skin, headache, fast heartbeat, feeling sick, feeling very hungry, changes in vision, feeling sleepy, feeling weak, being nervous, being anxious, confusion, difficulty concentrating and shaking (tremor). Your doctor will tell you how to treat low blood sugar and what to do if you notice these warning signs
Problems affecting the stomach and intestines, such as indigestion (dyspepsia), inflammation in the lining of the stomach (gastritis), stomach discomfort, upper stomach pain, heartburn, feeling bloated, wind (flatulence), belching and dry mouth
Difficulty sleeping (insomnia). This usually occurs in the first 3 months of treatment
Local reactions around the injection site, such as bruising, pain, irritation, itching and rash
Feeling weak or tired
Changed sense of taste
Increase of pancreatic enzymes, such as lipase amylase
Uncommon side effects (may affect up to 1 in 100 people)
Dehydration – more likely to occur at the start of treatment and may be due to being sick, having diarrhoea or nausea making you drink & eat less
Thyroid reactions such as goitres or nodules
Allergic reactions such as skin rash
Generally feeling unwell
Faster pulse rate
Delay in the emptying of the stomach
Inflamed gall bladder
Rare side effects (may affect up to 1 in 1,000 people)
Reduced kidney function
Acute kidney failure. Signs may include reduction in urine volume, metallic taste in mouth & easily bruising
For complete details about all side effects always read the Patient Information Leaflet.
The information we provide to our patients is based on the information provided by the manufacturer of the medication. You can access this either here https://www.saxenda.com/about-saxenda/side-effects.html or here for a more in-depth summary https://www.novo-pi.com/saxenda.pdf#guide. This information is based on the latest and best, current evidence.
How much does Saxenda cost?
Saxenda comes in a 3ml pre-filled injection pen and costs from £60 per pen. You have the choice of buying between one and five pens. When you first start Saxenda, a single pen will last 17 days.
Is Saxenda suitable for me?
Saxenda should only be used by adults who have a body mass index (BMI) of 30 or more, or 27 or more and a weight related medical problem such as high blood pressure or type 2 diabetes. Saxenda is not a treatment for diabetes.
Saxenda is not recommended for those with liver disease, kidney disease or heart failure. It shoud not be used by those with severe stomach or gut problems or inflammatory bowel disease. If you have a thyroid disease, you should consult our doctors before using Saxenda.
What is Saxenda®?
Saxenda® (liraglutide) injection 3 mg is an injectable prescription medicine that may help some adults with excess weight (BMI ≥27) who also have weight-related medical problems or obesity (BMI ≥30) lose weight and keep the weight off. Saxenda® should be used with a reduced-calorie meal plan and increased physical activity.
- Saxenda® is not for the treatment of type 2 diabetes
- Saxenda® and Victoza® have the same active ingredient, liraglutide, and should not be used together
- Saxenda® should not be used with other GLP-1 receptor agonist medicines
- Saxenda® and insulin should not be used together
- It is not known if Saxenda® is safe and effective when taken with other prescription, over-the-counter, or herbal weight-loss products
- It is not known if Saxenda® changes your risk of heart problems or stroke or of death due to heart problems or stroke
- It is not known if Saxenda® can be used safely in people who have had pancreatitis
- It is not known if Saxenda® is safe and effective in children under 18 years of age. Saxenda® is not recommended for use in children
How Does Saxenda® Work?
Saxenda® addresses one of your body's natural responses to weight loss.
- Your body naturally produces an appetite hormone known as glucagon-like-peptide (GLP-1) that helps to regulate your hunger
- Saxenda® works like GLP-1 by regulating your appetite, which can lead to eating fewer calories and losing weight
- Saxenda® is NOT a stimulant
What is my BMI?
Your Body Mass Index (BMI) can be determined by inputting your height and weight using a BMI Calculator like the one found on the NHS website.
Can I Use Saxenda® If I have a Weight Related Condition?
Reducing your waistline isn’t the only impact of weight loss. Taking off weight and keeping it off may help improve conditions such as high blood pressure and high cholesterol levels. Ask your health care provider about Saxenda®
Saxenda® is not indicated for the treatment of high blood pressure or high cholesterol. It is not known if Saxenda® changes your risk of heart problems or stroke or of death due to heart problems or stroke.
While you are at rest, Saxenda® can increase your heart rate. Tell your health care provider if you feel your heart racing or pounding in your chest and it lasts for several minutes while taking Saxenda®.
How Long Should I Use Saxenda® For?
Chronic conditions such as obesity often require longer treatments. Your treatment will begin and after 4 months you must have a review with your prescriber to see if you would need further treatment and if you should have your prescriptions renewed.
Where on my Body Should I Inject Saxenda®?
You should inject your dose under your skin (subcutaneous injection) in your stomach area (abdomen) upper leg (thigh) or upper arm. It is important to remember to rotate your injection sites regularly so that you are not injecting into the same area. Injecting into the same area can lead to a condition called lipohypertrophy, which is an accumulation of fat at the site where you have repeatedly injected. Do not inject into a vein or muscle.
What Is The Dosing Schedule For Saxenda®?
The starting dosage is 0.6 mg per day for 1 week. You should increase the dose each week until the dose of 3 mg is reached, as prescribed. The dosing schedule is designed to help minimize gastrointestinal side effects. If you start with a sample pen, you will need a prescription in order to complete the dose escalation.
Does Saxenda® Need to be Taken at a Specific Time?
Saxenda® can be taken at any time of day and it does not matter if you have had a meal or not. Once you start taking the medication, you should however try to take it daily at the same time.
How Do I Handle and Dispose of The Needle?
After you have completed your injection, carefully remove the needle from the pen. To avoid needlesticks, do not put the needle cap back on the needle. Place the needle in the sharps bin provided by Cloud Pharmacy with your order immediately to reduce the risk of needlesticks. Put the pen cap back on your pen after each use to protect Saxenda® from light. Do not throw away used needles in household trash or recycling bins.
How Long Does Each Pen Last?
Once you work your way up to the 3mg daily dose, each pen will lust 6-days.
How Should Saxenda® Be Stored?
Store new, unused Saxenda® pens in the refrigerator between 36°F and 46°F (2°C to 8°C). After first use, store in a refrigerator or at room temperature between 59°F and 86°F (15°C to 30°C). Pens in use should be thrown away after 30 days even if they still have Saxenda® left in them. Don’t freeze Saxenda®. Saxenda® that has been frozen must not be used.
Who Should Not Take Saxenda®?
Do NOT use Saxenda® If:
- You or any of your family have a history of MTC
- You have MEN 2. This is a disease where people have tumors in more than one gland in their body
- You are allergic to liraglutide or any of the ingredients in Saxenda®. Symptoms of a serious allergic reaction may include: swelling of your face, lips, tongue, or throat, fainting or feeling dizzy, very rapid heartbeat, problems breathing or swallowing, and severe rash or itching
Talk with your health care provider if you are not sure if you are pregnant or planning to become pregnant. Saxenda® may harm your unborn baby
Before taking Saxenda®, tell your healthcare provider about all of your medical conditions.
Can I Use The Same Needle More Than One Time?
No, you should never use the needle more than once. You should use a needle every time you take a new dose. Using the same needle can lead to increased risk of infection and pain. After each use, the needle becomes more and more blunt, meaning injecting more than once can cause injury to the area which you are injecting.
When I Order Saxenda® Am I Provided With Needles and Sharps Disposal?
Yes, if you do decide to choose this treatment, we will provide you with the correct amount of needles and sharps bin with your order.