Mysimba Tablets

  • mysimba weight loss

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Fastest delivery available: 19/07/2024

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Pricing and quantity options

Orlistat Capsules (120mg)

Quantities 120mg
42 £17.39
84 £33.98
168 £67.96
252 £98.99

Saxenda Weight Loss Pen

Quantities 3mg
1 £79.99
2 £159.99
3 £239.99
4 £318.99
5 £374.99

Saxenda Weight Loss Pen

Quantities 3mg
1 £79.99
2 £159.99
3 £239.99
4 £318.99
5 £374.99

Wegovy (Semaglutide) Weight Loss Injection

Quantities Weeks 1-4: 0.25mg
1 Month £159.00
Quantities Weeks 5-8: 0.5mg
1 Month £159.00
Quantities Weeks 9-12: 1.0mg
1 Month £165.00
Quantities Weeks 13-16: 1.7mg
1 Month £219.00
Quantities Weeks 17 onwards: 2.4mg
1 Month £259.00
Quantities Starter Packs
2 Months - 0.25mg & 0.5mg £319.00
3 Months - 0.25mg & 0.5mg & 1.0mg £469.00

Mysimba Tablets

Quantities 8mg/90mg
112 £109.00

Xenical 120mg Capsules

Quantities 120mg
42 £29.98
84 £44.50
168 £87.99
252 £130.50

Mounjaro Weight Loss Injection

Quantities Starting Dose 2.5mg
1 Month £138.99
Quantities 5mg
1 Month £138.99
Quantities 7.5mg
1 Month £164.99
Quantities 10mg
1 Month £168.99
Quantities 12.5mg
1 Month £194.99
Quantities 15mg
1 Month £198.99
Quantities Starter Pack 2.5mg & 5mg
2 Month Starter Pack £289.00
Quantities Starter Pack 2.5mg & 5mg & 7.5mg
3 Month Starter Pack £449.99
Registered UK Pharmacy number 9012073
Please note: This page is only to be used as a reference of our price for this medication. If you are approved you will be offered treatment for you and the prescriber to jointly consider. However, the final decision will always be the prescriber's.

Medication features

Mysimba is an effective weight loss tablet that effectively helps those who are obese or overweight lose weight. This tablet, in conjunction with a healthy diet and regular exercise, is proven to help patients lose weight. 

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  • Helps you lose weight
  • Works by suppressing the appetite
  • Slow-release tablet
  • 8mg Naltrexone and 90mg bupropion in each tablet
  • Free online consultation is available
  • Next-day delivery in the UK is available

Mysimba Tablets Summary

Medicine TypeOpiate antagonists and antidepressants 
Mechanism of ActionInteracts with the central nervous system, signaling to the brain that the stomach is full, reducing appetite and cravings. 
Active IngredientNaltrexone and bupropion 
Effective Within1-3 months 
Pack Size112 tablets
Strength8mg Naltrexone and 90mg bupropion

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About Mysimba Tablets

Mysimba tablets are an approved weight loss treatment that helps those that are obese or generally overweight. They are an effective option for aiding in weight loss when other options have failed. Mysimba is a slow-release tablet containing two active ingredients: naltrexone and bupropion.

Mysimba, in combination with lifestyle changes, including a reduced-calorie diet and regular exercise, can help you lose weight. Improving your quality of life and decreasing the risk of developing weight-related health conditions such as heart disease, stroke, high blood pressure, and type 2 diabetes.

Cloud Pharmacy offered free and fast online consultations before dispensing Mysimba tablets.

Where can You Buy Mysimba in the UK?

Mysimba is a prescription-only medication, meaning that you cannot purchase it without a prescription from a registered and licensed healthcare provider. Alternatively, you can complete a free online consultation with a Cloud Pharmacy pharmacist who is able to dispense Mysimba.

Cloud Pharmacy is a UK-registered online pharmacy that can provide guidance on which weight loss medication will work best for you.

Mysimba Alternatives

During your free online consultation, the following alternatives to Mysimba slow-release tablets may be suggested:

Weight loss Injections

Weight Loss Pills

Mysimba Reviews

Mysimba tablet reviews are generally positive. Some reviewers commented that they experienced a reduction in their appetite, which resulted in them eating less throughout the day. Other reviewers experienced strong side effects that disappeared as time passed.

Informational Sources

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How to Take Mysimba

Mysimba tablets should be swallowed whole with water and can be taken with, or after food. Never chew, crush or split Mysimba tablets – this can alter the release of the active ingredients into the body.

Follow your doctor’s advice on Mysimba dosage. Your dose will typically be increased over a period of four weeks, by which time you will reach your ‘maintenance dose’. Mysimba dosage is usually increased as follows:

  • Week 1 – one tablet taken in the morning
  • Week 2 – one tablet taken in the morning, and one tablet taken in the evening
  • Week 3 – two tablets taken in the morning, and one tablet taken in the evening
  • Week 4 – two tablets taken in the morning, and two tablets taken in the evening

Once you reach Week 4, you will continue with the Week 4 dosage – this is known as the ‘maintenance dose’; the maximum recommended Mysimba dose. You should always follow your doctor’s instructions for taking Mysimba.

How Long Does Mysimba Take To Work?

If you have not lost at least 5% of your body weight at 16 weeks, your doctor will consider if you should stop taking Mysimba. Note that you can achieve the best results when combining Mysimba with a healthy lifestyle and balanced diet.

Guidance from Orexigen Therapeutics, the company which manufactures Mysimba, advises that after eight weeks of treatment, improvements can be seen. Research conducted with over 4,500 overweight or obese patients shows that Mysimba has a significant effect on weight loss, compared to patients who were given a placebo.

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Mysimba Ingredients 

Active Ingredient: Naltrexone hydrochloride and bupropion hydrochloride 

  • Each tablet contains 8mg of naltrexone hydrochloride and 90mg of bupropion hydrochloride 

Other ingredients: 

  • Tablet core: microcrystalline cellulose, lactose anhydrous, hydroxypropyl cellulose, lactose monohydrate, cysteine hydrochloride, magnesium stearate, crospovidone type A, hypromellose, edetate disodium, colloidal silicon dioxide, and indigo carmine aluminium lake (E132)
  • Film-coating: titanium dioxide (E171), poly(vinyl alcohol), macrogol (3350) talc, and indigo carmine aluminium lake (E132)

Mysimba Side Effects
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Mysimba Side Effects

As with all medications, there are reported side effects that occur, although not everyone may experience them. Below, we take a look at side effects to keep an eye out for

Serious side effects of Mysimba 

  • Suicidal thoughts and feeling depressed
  • Erythema multiforme and Stevens-Johnson Syndrome 
  • Seizures (fits) 
  • Serotonin syndrome 
  • Lupus skin rash or worsening lupus symptoms 
  • Rhabdomyolysis 
  • Acute generalised exanthematous pustulosis 

Seek immediate medical attention if you experience any of these serious side effects.

Common Side Effects of Mysimba 

  • Nausea 
  • Vomiting 
  • Headache 
  • Constipation 
  • Anxiety 
  • Difficulty concentrating 
  • Dizziness 
  • Feeling shaky 
  • Difficulty falling asleep 
  • Dysgeusia (changes in the taste of food) 
  • Dry mouth 
  • Hair loss (alopecia) 
  • Irritability 
  • Feeling jittery 
  • Increased blood pressure 
  • Hot flush 
  • Fast and irregular heartbeat 
  • Tinnitus (ringing in the ears) 
  • Pain in the abdomen 
  • Rash, itching 
  • Pain in the upper part of the abdomen 

Mysimba side effects should disappear if you are taking the medication exactly as prescribed and sticking to your recommended diet. Talk to your doctor or pharmacist if any side effects persist and do not disappear. 

Less common side effects of Mysimba 

  • Hypersensitivity 
  • Loss of memory 
  • Motion sickness 
  • Feeling nervous
  • Balance disorder 
  • Burping 
  • Hives 
  • Abnormal dreams 
  • Indigestion 
  • Abdominal discomfort 
  • Inflammation of the gallbladder 
  • Chest pain 
  • Thirst and feeling hot 
  • Difficulty in getting or keeping an erection 
  • Increased creatinine levels in the blood
  • Increased liver enzymes and bilirubin levels 
  • Increased appetite and weight gain 

Rare side effects of Mysimba

  • Hallucinations 
  • Fainting, loss of consciousness 
  • Swelling of the face, eyelids, tongue, throat, or lips 
  • Decreased hematocrit 
  • Low amount of lymphocytes (white blood cells) 
  • Dental cavities 
  • Toothache 
    Injury to the liver
  • Irregular menstrual cycle 
  • Jaw pain 
  • Pain in the lower part of the abdomen 
  • Passing fresh blood through the anus 
  • Fits 
  • Hernia 
  • Coldness of the hands or feet

Although these side effects are uncommon, if you experience any of them, seek medical help immediately by either going to A&E or calling 999. If you have any concerns about Mysimba or would like to know more about possible side effects, talk to your doctor or pharmacist. 

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Mysimba Warnings

Before taking Mysimba tablets, discuss with your doctor or pharmacist:

  • If you have high blood pressure
  • If you have uncontrolled coronary artery disease
  • If you have a condition that affects the circulation of blood to the brain (cerebrovascular disease)
  • If you have kidney problems
  • If you have liver problems
  • If you have a history of mania
  • If you have Brugada syndrome
  • If you have a history of mental health problems, including contemplating suicide, depression, panic attacks, or have attempted suicide

Mysimba Drug Interactions

Discuss with your pharmacist or doctor if any of the following points apply to you:

Do not take Mysimba with:

  • Opiates and opiate-containing medication
  • Monoamine oxidase inhibitors

Tell your doctor if you are taking any of the following medications:

  • Medicines to help you sleep
  • Medicines for depression and other mental health problems
  • Steroids
  • Medicines used to prevent malaria
  • Quinolines
  • Tramadol
  • Medicines to lower blood sugar levels
  • Antihistamines
  • Theophylline
  • Medicines used to treat high blood pressure
  • Medicines used to treat Parkinson’s disease
  • Medicines used to treat HIV infections and AIDs
  • Medicines used to treat epilepsy
  • Ticlopidine and clopidogrel
  • Medicines used to treat cancer
  • Medicines used to treat irregular heart rhythm

Patient Information Leaflet
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Mysimba Patient Information Leaflet

For more information on Mysimba medication, take a look at the patient information leaflet below:

Mysimba Tablets FAQs
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Is Mysimba good for weight loss?

Mysimba is a safe and effective weight loss medication for those living with obesity.

What are the most common side effects of Mysimba?

The most common side effects of Mysimba are vomiting and nausea, dry mouth, constipation, and dizziness.

Is Mysimba the same as Contrave?

Yes. Contrave and Mysimba are the same medication containing bupropion and naltrexone in a sustained-release form. 

Is Mysimba effective at helping patients lose weight?

In a study, about 13-22% of participants taking Mysimba had at least a 10% reduction in weight, while 5-6% of participants taking a placebo also achieved a 10% reduction in weight. 

Does Mysimba work immediately?

Once you have taken your first dose of Mysimba, it starts working; however, it can take a few weeks up to 16 weeks to see the full effects of this weight loss medication. After 16 weeks, you can lose 5% or more of your starting weight. 

Does Mysimba affect sleep?

A very common side effect (affects more than 1 in 10 people) of Mysimba is insomnia.

Does Mysimba give you energy?

One of the active ingredients in Mysimba, bupropion, is an antidepressant that can improve energy levels and mood in some individuals. 

What happens when you stop taking Mysimba?

Once you have stopped Mysimba treatment, you may find that you are more sensitive to low doses of opiate medications. Always take Mysimba as prescribed, and do not stop it without instruction from your healthcare provider.

What is the difference between Mysimba and Orlistat?

Orlistat is a lipase inhibitor, meaning that it stops the body from absorbing fat. At the same time, Mysimba affects the receptors found in your brain. It affects the signals that play a role in energy levels and appetite.

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8mg/90mg 112 £109.00