Spedra (Avanafil) Tablets (50mg, 100mg & 200mg)

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Fastest delivery available: 06/12/2023

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Pricing and quantity options

Tadalafil Tablets

Quantities 10mg
4 £8.49
8 £17.50
16 £23.99
32 £45.95
Quantities 20mg
4 £8.99
8 £17.50
16 £23.99
32 £45.99
Quantities 2.5mg
28 £18.99
56 £32.99
84 £40.99
Quantities 5mg
28 £24.99
56 £42.99
84 £63.99

Sildenafil Tablets (Generic Viagra)

Quantities 25mg
1 £0.47
4 £6.99
8 £14.99
16 £19.99
32 £24.99
Quantities 100mg
4 £9.99
8 £19.99
16 £29.99
32 £59.99
Quantities 50mg
4 £11.99
8 £19.99
16 £34.98
32 £48.99

Viagra Connect (50mg) Tablets

Quantities 50mg
4 £20.99
8 £34.99
12 £60.99
16 £79.99

Viagra Tablets (25mg, 50mg, 100mg)

Quantities 25mg
4 £24.99
8 £43.99
16 £79.99
32 £139.99
Quantities 50mg
4 £29.99
8 £57.99
16 £99.99
32 £149.99
Quantities 100mg
4 £29.99
8 £57.99
16 £99.99
32 £149.99

Eropid 50mg Tablets (Sildenafil)

Quantities 50mg
4 £13.49
8 £23.95
12 £33.99
16 £43.99
32 £79.99

Spedra (Avanafil) Tablets (50mg, 100mg & 200mg)

Quantities 50mg
4 £28.99
8 £49.99
12 £68.99
16 £88.99
Quantities 100mg
4 £31.99
8 £59.99
12 £80.99
16 £99.99
Quantities 200mg
4 £41.99
8 £72.99
12 £107.99
16 £140.99

Cialis (Tadalafil) Tablets

Quantities 20mg
4 £38.99
8 £73.99
16 £135.99
32 £254.99
Quantities 10mg
4 £38.99
8 £73.99
16 £135.99
32 £254.99
Quantities 2.5mg
28 £70.99
56 £139.99
84 £201.95
Quantities 5mg
28 £70.99
56 £139.99
84 £201.95

Vardenafil Tablets (5mg, 10mg & 20mg)

Quantities 5mg
4 £16.99
8 £32.98
16 £63.98
32 £123.99
Quantities 10mg
4 £21.97
8 £39.98
16 £67.99
32 £109.99
Quantities 20mg
4 £25.99
8 £49.99
16 £79.99
32 £105.99

Cialis Together Tablets

Quantities 10mg
4 £18.99
8 £33.99
More Information
Registered UK Pharmacy number 9010794
Please note: This page is only to be used as a reference of our price for this medication. If you are approved you will be offered treatment for you and the prescriber to jointly consider. However, the final decision will always be the prescriber's.
  • Contains Avanafil
  • Works Within 20 Minutes
  • Works For 4-5 hours
  • Next Day Delivery Available
  • Discreetly Packaged

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What Are Spedra Tablets?

Spedra tablets are a type of medication that are taken for Erectile Dysfunction (ED). Spedra works similar to how Sildenafil works. Spedra works by promoting blood flow towards the penis, which results in heightened ability yo maintaing erections to help cure your ED. The blood flow will usually only occur during sexual stimulation, meaning you can still enjoy foreplay whilst taking Spedra Tablets. 

Spedra comes in three different strenghts, 50mg, 100mg and 200mg. It is recommended that you start on 100mg, however, other strenghts can be prescribed depending on what you need, by our UK qualified, UK-based prescriber. 

Avanafil for ED Treatment

The active ingreadient in Spedra Tablets is the drug Avanafil- avanafil is also sold under the brand name 'Stendra' in the USA. Avanafil is part of a class of drugs known as PDE-5 inhibitors. PDE-5 is an enzyme, which when inhibited will increase blood flow to the penis when you become aroused and therefore you are able to achieve and maintain an erection for a longer period of time. Other PDE-5 inhibitors are Sildenafil, Tadalafil,Viagra and Eropid.

Can You Get Avanafil in the UK?

Avanafil is available in the UK. Avanafil is a prescription medication and therefore cannot be purchased without a prescription from a GP or a registered online pharmacy, such as Cloud Pharmacy. Before purchasing Avanafil (Spedra) tablets, you must cmomplete a consultation, which will be reviewed by a member of our medical team. If this item is right for you, then a prescription wil be generated and the tablets will be sent out to you from the pharmacy. 

What is Spedra 100mg?

Spedra comes in a vairety of strenghts. These strengths are 50mg, 100mg and 200mg. Clinical guidance suggests that you should start taking Spedra Tablets at a strengh of 100mg. 

Spedra 200mg is the highest strenght of Spedra that is available. This strenght is reserved for those that have tried lower strengths or other ED cures that have not worked. 

Spedra 200mg tablets should be effective and strong enough to treat most cases of ED. However, like all ED medication, there is a possibility of little to no effect, especially if it is the first time the medicine is being used. If a certain dose of Spedra is not working, it is recommended that you try at least eight times before switching to a different strength of Spedra or medicine. 

If you notice side effects of Spedra such as headaches or flushing and persist after uses the medicine multiple times then you should stop using Spedra and switch to a different ED medicine or reduce your dose of Spedra. 

How Long Does Spedra Take To Work?

Spedra is one of the fastest solutioins for ED available- it can take as little as 20 minutes and this can last for up to 4 or 5 hours. If you have eaten an hour before taking Spedra, it may take up to 90 minutes for the medication to work. It is therefore recommended you have a low fat meal 2-3 hours before taking Spedra.

Does Spedra Work?

Spedra works by treating the physical causes of ED that prevent men from achieving and maintaining an erection (reduced blood flow to the penis because of narrowing of areteries). ED can also be caused by psychological reasons such as performance anxiety or depression. It is possible that Spedra can help achieve an erection if the symptoms are psychological, however it is not as successful in these cases (like all ED medication). It is recommended that you use ED medication and speak to a doctor or therapist for longer term solution.

Does Spedra Take Effect Faster Than Viagra?

Spedra is a much quicker treatment than Viagra — it can take as little as 20 minutes to take effect. It is normally recommended that you take one Spedra tablet around 30 minutes before sex (and for some men, it can work as quickly as 15 minutes after consumption, particularly if you take it on an empty stomach).

Viagra, on the other hand, needs to be taken one hour before sex as it is unlikely to work in a shorter period of time.

If you take Spedra on a full stomach after a large fatty meal — in this instance it can take as long as 90 minutes to have the desired effect.

Does Spedra Last Longer Than Viagra

It is a draw between the Viagra and Spedra. Both of these ED treatments last a similar amount of time — roughly 4-5 hours.

It is worth mentioning that this does not mean that you will have an erection for 5 hours straight, but that your ability to achieve and maintain an erection will increase during this time.

Is Spedra as Effective as Viagra?

In clinical trials, Viagra provides a very effective treatment for erectile dysfunction in about 80% of men, whereas Spedra only proivdes effective treatment for about 60% of men.

It depends what you deem to be more important to you, if you want a better chance of getting an erection then Viagra is likely your first choice, however if you are looking to achieve and maintain an erection for up to FOUR times quicker than Viagra, then Spedra should be your choice.

Can I Drink Alcohol With Spedra?

It is recommended that you do NOT drink alcohol whilst taking Spedra.

However, it is not dangerous to drink alcohol at the same time as taking Spedra. Drinking alcohol and taking Spedra amy increase your heart rate and lower your blood pressure. You might also feel quite dizzy (especially when standing up), have a headache, or feel your hear beating particulary quickly. or strongly in your chest (palpitations).

Drinking alcohol amy also reduce your ability to achieve an erection, meaning drinking alcohol may have a counter-productive effect when taking Spedra.

What is The Best Erectile Dysfunction Treatment?

Tadalafil - Best if you want a long-lasting ED treatment, it is the generic brand of Cialis and can last for up to 36 hours.

Viagra - Best if you are looking for a well known ED treatment that can last for up to 4 or 5 hours

Spedra - Best if you want a fast acting ED treatment

Sildenafil - Best if you are looking for a cheaper alternative to Viagra.

Viagra Connect - For those that do NOT have a prescription for ED medication

Eropid - A cheaper alternative to Viagra Connect for those that do not have a prescription

Spedra (Avanafil) Reviews

Spedra has a very mixed bag of reviews, whilst some patients find that it is not as effective as medications like tadalafil which boasts an incredibly long lasting effect, some users much prefer it to medications such as Viagra or Sildenafil because of how quickly it takes effect compared to the traditional ED medications. One reviwer left the following review: 

"Love this new pill! Less side effects than Viagra and Cialis, last twice as long as Viagra and start in as little as 15 minutes. I've used Viagra as well as Cialis and Stendra is better in all aspects hands down!"

Spedra (Avanafil) Summary

Spedra Dose

Take ONE tablet 15-30 minutes before sexual activity.

Spedra Duration of ActionSpedra can last for 4-6 hours
Spedra Mechanism of Action

Spedra inhibits an enzyme (protein) that is responsible for causing blood vessels to contract.

Inhibiting this protein allows for increased blood flow to the penis, resulting in longer lasting and firmer erections.

Spedra Side-EffectsSide effects are not very common, however they can include: Nausea, vomiting and diarrhoea. Spedra can also cause headaches, facial flushing, nasal congestion, a pounding heartbeat and blurred vision
Spedra and NitratesSpedra CANNOT be prescribed if you are taking medications that are nitrate based such as GTN spray or isosorbide tablets for angine.
Spedra Price

Prices start from £28.99

Side Effects
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Spedra Side Effects

Many people who take Spedra do not experience any side effects at all. However, if you have never taken this ED medication before, or if you take the stronger 200mg dosage of Spedra, you are more likely to experience side effects.

The following Spedra side effects are common, which means they may appear in up to 1 in 10 people:

  • Flushing 
  • Nasal Congestion
  • Headache

Spedra also has a small risk of nausea, vomiting, diarrhoea and a skin rash. As with all meidcine. The patient informatuion leaflet is enclosed with the medication which will detail a full and extensive list of possible side effects.

Stop taking spedra immediately and see a doctor if you experience any of the following serious side effects: 

  • Blurred vision
  • Sudden decrease or loss of vision in one or both eyes
  • Sudden decrease or loss of hearing (you may also feel dizzy or have ringing in your ears)
  • An erection that will not go away (known as priapism). If you get an erection that lasts more than 4 hours, this must be treated as soon as possible or lasting damage can happen to your penis (including not being able to get erections)

It may be that you need urgent medical treatment, so you should see a medical professional as soon as possible.

If you experience any of the above side effects, notice anything else unusual or you are concerned about using Spedra, consult with a doctor or pharmacist.


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Spedra (Avanafil) Tablet Warnings

Do NOT take Spedra:

  • If you are taking “nitrate” medicines for chest pain (angina), such as amyl nitrite or glyceryl trinitrate. Spedra can increase the effects of these medicines and severely lower your blood pressure
  • If you are allergic to avanafil or any of the other ingredients of this medicine (listed in section 6)
  • If you are taking medicines for HIV or AIDS such as ritonavir, indinavir, saquinavir, nelfinavir or atazanavir
  • If you have a serious cardiac problem
  • If you are taking medicines for fungal infections such as ketoconazole, itraconazole or voriconazole or certain antibiotics for bacterial infections, such as clarithromycin or telithromycin
  • If you have had a stroke or heart attack in the last 6 months
  • If you have an irregular heartbeat (“arrhythmia”) or heart problems that run in your family, as shown on a heart tracing (ECG)
  • If you have low blood pressure or high blood pressure not controlled by medicines
  • If you have chest pain (angina) or you get chest pain during sexual intercourse
  • If you have a serious liver or kidney problem
  • If you have loss of vision in one eye due to not enough blood getting to your eye (non-arteritic ischemic optic neuropathy [NAION])
  • If certain serious eye problems run in your family (such as retinitis pigmentosa).

Do NOT take Spedra if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before taking Spedra.

Spedra Warning and Precautions

Talk to your doctor or pharmacist before taking Spedra:

  • if you suffer from priapism, that is a persistent erection lasting 4 hours or more. This can happen in men with conditions like sickle cell disease, multiple myeloma or leukaemia.
  • if you have heart trouble. It may be risky for you to have sexual intercourse
  • If you have a physical condition that affects the shape of your penis (such as angulation, Peyronie’s disease or cavernosal fibrosis)
  • If you have any bleeding disorder or active peptic ulceration.

If any of the above applies to you, talk to your doctor or pharmacist before taking Spedra. Check with your doctor or pharmacist if you are not sure.

Problems with sight or hearing

Some men taking medicines like Spedra have had problems with their sight and hearing – see “Serious side effects” in section 4 for more details. It is not known if these problems are related directly to Spedra, other diseases that you may have or a combination of factors.

Patient Information Leaflet
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Spedra 50mg, 100mg, 200mg Tablet Patient Information Leaflet

For more information about Spedra Tablets, please take a look at the information leaflet below. It is important you read the Patient Information Leaflet (PIL) before taking Spedra:

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How Does Spedra Work?

Spedra does not initiate sexual arousal; it is only effective if you are aroused sexually already.

Spedra is one of a class of drugs known as PDE-5 (Phosphodiesterase type 5) inhibitors. Like other medications in this class, such as sildenafil or tadalafil, it works by stopped this protein (PDE-5) from binding to blood vessels in the penis. Preventing this enzyme or inhibiting it will allow for increased blood flow to the penis, thus allowing for longer lasting and firmer erections.

Is Spedra Effective?

Clinical studies have shown that when Spedra is compared to a Placebo and the other drugs in the same class, the results indicated a significant improvement in preventing the effects of Erectile Dysfunction (ED).

The proposed advantage of Spedra is that it has very quick onset of action when compared to other PDE5 inhibitors. It is absorbed rapidly, reaching a maximum concentration in about 30–45 minutes. Roughly two-thirds of the trial participants were able to engage in sexual activity within 15 minutes.

Although Spedra has been established as a safe, relaible and effective medication for ED, it may not be appropriate for everyone who suffers from the condition and it might not work.

How Does Spedra Affect Blood Pressure?

Spedra can lower blood pressure slightly; this is not a problem for the majority of men using this treatment. The prime issue is Spedra's effects can be perpetuated if taken with a nitrate drug (commonly prescribed for angina) such as GTN spray or isosorbide mononitrate.

If you take Spedra with a nitrate, it can lower your blood pressure to an extent that could prove fatal. You must never take Spedra if you are taking a nitrate.

Can I Take Spedra if I Have a Heart Condition?

If you suffer from any hear condition, you must consult with your doctor for a full check-up to see if Spedra is suitable for you or if you can take it with a heart condition.

Can Women Take Spedra?

Spedra is a medication for erectile dysfunction and therefore it cannot be taken by women. There are no medications for ED that are licensed or can/should be taken by women.

How Long Does it Take for Spedra to Work?

A single Spedra tablet should be taken 15-30 minutes beofre any sexual activity. On average it usually takes 30 minutes to start working. If you take Spedra with food, it can take longer to work than if taken on an empty stomach.

The effects of Spedra can last for as long as 4-6 hours. This does not mean you will have an erection continuously for that period of time, it just means you will find the ability to get and maintain an erection easily.

How Often Should I Take Spedra?

You should not take more than a single dose of Spedra in a 24 hour period.

Where Can I Buy Spedra?

Spedra, like most other drugs in it's class is a prescription only medication (POM) and therefore it can only be acquried by either getting a prescription from your doctor or by using a registered and regulated online doctor or pharmacy service. Online services can provide you with a prescription and also have the item sent to your door.

Why Are There Different Strengths?

Spedra comes in three different doses / strengths. It comes in 50mg, 100mg and 200mg tablets. Some men can respond to lower doses of Spedra whilst some may need higher doses. Another reason the doses are different is because some men may be taking medication that can interact with Spedra so a dose adjustment may be required.

What Dose of Spedra Should I Take?

It is recommended that men start at a dose of 100mg of Spedra. If you experience side effects then the advice is to drop to 50mg and if you experience no effect then you are advised to increase the dose to 200mg.

What Happens if it Does Not Work The First Time?

It is advised that you take the medication at least EIGHT times before concluding whether or not the medication works. On some occasions the medication may not work the first time around.

Who Cannot Use Spedra?

Men who have any of the following conditions should also avoid taking it: severe heart or liver problems, recent stroke or heart attack, low blood pressure, certain rare inherited eye diseases.

Does Spedra Cure The Underlying Cause of ED?

Spedra, 'nor any ED medication, can resolve the underlying cause of impotence. Using medication such as Spedra may help in breaking the cycle associated with ED however, suhc as the feeling of failure and anxiety when you cannot achieve an erection. If the reason you cannot achieve an erection is due to a health condition like diabetes where your blood vessels shrink, then again, the medication will not be a cure but it will help you get an erection.

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Confirm Spedra (Avanafil) Tablets (50mg, 100mg & 200mg) treatment selection

50mg 4 £28.99
50mg 8 £49.99
50mg 12 £68.99
50mg 16 £88.99
100mg 4 £31.99
100mg 8 £59.99
100mg 12 £80.99
100mg 16 £99.99
200mg 4 £41.99
200mg 8 £72.99
200mg 12 £107.99
200mg 16 £140.99