Spedra Reviews: What Real Users Think

Erectile dysfunction (ED), or impotence, is a common sexual disorder, especially in men over the age of 40. ED is caused by many factors, both physical and psychological. It may be embarrassing to discuss impotence or ED with your pharmacist or GP, but it is important that you do so to receive the best treatment. 

There are many effective treatment options, such as Spedra (avanafil) tablets, that help you achieve and sustain an erection when sexually stimulated. These medications require a prescription, which you can get after a quick consultation with a pharmacist at Cloud Pharmacy. 

To help you decide if Spedra is a good choice for you, this article explores what this popular ED medication is, how it works and real-life Spedra reviews.

Spedra Overview: What is it, and How Do You Use it? 

Active Ingredients 

The active ingredient in Spedra is avanafil

How Does Spedra Work? 

The active ingredient in Spedra, avanafil, belongs to a class of drugs called phosphodiesterase 5 (PDE5) inhibitors. PDE5 inhibitors block the enzyme PDE5 from breaking down cyclic guanosine monophosphate. The smooth muscles of the penis begin to relax, which leads to an increase in blood flow, causing an erection. 

PDE5 inhibitors, such as Spedra, are a temporary treatment for ED and only work when the user is sexually aroused. 

How Long Does Spedra Take to Work? 

Spedra is one of the fastest-acting prescription treatments for ED. Once a dose is taken, it can begin to work in 20 minutes. Spedra can last in the bloodstream for up to 4 or 5 hours. If you take Spedra after a big meal, it can take up to 90 minutes to begin working. The effects of Spedra only occur if you are sexually stimulated. 

How Much Spedra Can be Prescribed on the NHS?

Spedra is only prescribed on the NHS if you have erectile dysfunction with special medical conditions such as: 

  • Diabetes 
  • Kidney failure 
  • Prostate cancer 
  • Multiple sclerosis 
  • Parkinson’s disease 
  • Spina bifida 
  • Spinal cord injury 

Dosage and Usage Recommendations 

Spedra (avanafil) is available in 50mg, 100mg and 200mg doses. The general recommended dose of Spedra is 100mg. The dose can be decreased or increased by your pharmacist or GP, depending on your needs. 

Do not take more than one dose of Spedra in a 24-hour period. 

How Does it Feel After Taking Spedra? 

After taking your prescribed dose of Spedra, you may experience mild side effects that should disappear after a couple of hours. If you have consumed alcohol, your chances of experiencing side effects are increased. 

After 20-30 minutes of taking Spedra, the effects should work if you are sexually aroused. Talk to your GP or pharmacist if, after a couple of tries, Spedra still doesn’t work as it should for you. 

Are There Any Known Side Effects of Spedra? 

As with any medication, there are known side effects that may occur when taking Spedra. However, not everyone may experience them. Common side effects of Spedra include: 

  • Flushing 
  • Headache 
  • Nasal congestion (runny or stuffy nose) 
  • Back pain 
  • Blurry vision 
  • Indigestion 
  • Dizziness 
  • Diarrhoea

Severe side effects of Spedra may include: 

  • Allergic reaction symptoms
  • Increased heart rate 
  • Rash
  • Chest pain 
  • Insomnia 
  • Premature ejaculation 
  • Priapism (and ejaculation that lasts 4 hours or longer)

If you have any severe side effects, seek emergency medical attention. Talk to your GP or pharmacist if you have persistent side effects that do not clear up. If you would like to know all the identified side effects of Spedra, you can find them in the Patient Information Leaflet.  

Interactions With Other Medications 

Before taking Spedra, tell your GP or pharmacist if you take any other prescription medications, supplements, vitamins or herbal remedies. You should avoid using Spedra if you take any of the following types of medications: 

  • Nitrates: These medications are used to treat heart conditions or chest pain. They include glyceryl trinitrate and amyl nitrate.
  • Protease Inhibitors: These medications, such as indinavir, nelfinavir and ritonavir, are used for treating HIV and AIDs.
  • Some Antibiotics: Antibiotics, such as erythromycin, clarithromycin and telithromycin, can interact negatively with avanafil.
  • Fungal Infection Medications: Ketoconazole, itraconazole and voriconazole are examples of fungal medications that interact with Spedra.
  • Alpha-Blockers: These medications are used to treat high blood pressure or prostate problems. 

Cost of Spedra 

Cloud Pharmacy stocks Spedra tablets in 50mg, 100mg, and 200mg doses, which can be purchased with a prescription. 

Dosage4 Tablets 8 Tablets 12 Tablets 16 Tablets
100mg £31.99£59.99£80.99£99.99
200mg £41.99£72.99£107.99£140.99

Spedra Summary

Active ingredientAvanafil
How it works Avanafil is a PDE5 inhibitor that promotes blood flow into the penis when the user is sexually aroused.
Dosage 50mg, 100mg, 200mg
Effectiveness Spedra begins working within 20-30 minutes and can last in the body for up to 4-5 hours.
Side effects
  • Headaches 
  • Facial flushing 
  • Vomiting 
  • Nausea 
  • Diarrhoea 
  • Nasal congestion 
  • Blurred vision
Interactions with other medication
  • Protease inhibitors 
  • Some antibiotics 
  • Alpha-blockers 
  • Nitrate medicines 
  • Fungal infection medication 
  • Other PDE5 inhibitors
Cost Starting from £28.99

Spedra Reviews 

Spedra reviews are mixed. Some users found Spedra was not as effective as other ED medications, such as tadalafil. Some users prefer Spedra due to its fast-acting effect. 

Key takeaways from Spedra reviews include: 

  • Minimal to no side effects were reported by users
  • Spedra is a fast-activating ED solution that can work within 20 minutes
  • Reviewers found Spedra was a reliable product
  • Reviewers found Spedra was extremely effective
  • Some reviewers found the long-lasting effects of tadalafil more beneficial than the fast-acting effects of Spedra

Branded vs. Generic: Which is Better? 

There is currently no generic version of Spedra. Using DrugPatentWatch®, the earliest possible date for a generic version is October 18, 2025.

Recent Spedra Research and Relevant Reading Material 

If you would like to know more about ED or impotence or would like to read more about Spedra (avanafil) tablets, we have compiled some resources below: 

Where Can you Buy Spedra in the UK?

Now that you’ve read Spedra reviews, you may be wondering where you can buy Spedra. 

You can only buy Spedra in the UK with a prescription. It is important to get any medication from a registered and licensed pharmacist, such as Cloud Pharmacy, to avoid counterfeits and ensure you are getting exactly what you need. 

You can get a prescription for Spedra after a quick online consultation with a registered pharmacist at Cloud Pharmacy. Simply fill out a quick eligibility check before your consultation to determine if Spedra is the best ED treatment for you. Once you have purchased your ED treatment, it is sent quickly to your UK address in confidential packaging. 

Spedra FAQs 

How Long Does Spedra 200mg last? 

Spedra 200mg can be effective in 20 minutes after taking it, and it can last in the bloodstream for 4-5 hours. For Spedra 200mg to work, you need to be sexually stimulated. 

Is Spedra Any Good? 

Spedra is an effective medication that treats ED or impotence in men. It is generally well tolerated, with minimal side effects that clear in 2 hours. 

There are mixed reviews of Spedra. Some users prefer its fast-acting ability, while others prefer other ED medications, such as tadalafil, as they last longer in the bloodstream.

Ultimately, your choice to use Spedra will depend on personal preference and individual needs. 

Is Spedra as Good as Viagra? 

Whether Spedra is as good as Viagra varies from person to person. In clinical trials, Spedra was found to provide effective treatment for ED or impotence in about 60% of men, while Viagra was found to be effective in about 80% of men. 

How Long Does Spedra 100mg Last? 

Once taken, Spedra 100mg can begin working within 20 minutes when sexually stimulated and can last in the bloodstream for 4-5 hours. 

What are the Doses of Spedra? 

The typical recommended dose of Spedra to treat ED is 100mg. Depending on how you react to the 100mg dose of Spedra, your pharmacist or GP can increase the dose to 200mg or decrease the dose to 50mg. 

It is important that you do not take more than one dose of Spedra in a 24-hour period. Talk to your pharmacist or GP if you have any concerns or questions about what dose of Spedra will work best for you. 

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