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Zyban works by impacting the equilibriums of certain chemicals that occur naturally inside the human brain. This prevents the harsh after-effects of smoking withdrawal symptoms and the urge to continue smoking.
- Effective Stop Smoking Medication
- Reduces Cravings and Withdrawal Symptoms
- Used often alongside nicotine replacements
What Is Zyban?
Zyban is a medication that is prescribed to people who are trying to stop smoking. Sometimes it can be prescribed for depression and seasonal affective disorder (SAD). Zyban contains 150 mg of the active ingredient bupropion hydrochloride and belongs to the antidepressants class of medications.
The tablets can reduce cravings for nicotine, as well as withdrawal symptoms including anxiety, irritability and restlessness. By being effective in helping people quit smoking, Zyban can reduce the risk of serious medical conditions such as lung disease, heart disease and cancer.
How Does Zyban Work?
The way in which Zyban works to reduce smoking urges is not completely understood. It is thought that the medication may help to restore the balance of specific neurotransmitters (natural chemicals) in the brain. In this way, it can affect the areas of the brain that play a role in addictive behaviour.
Zyban and Alcohol
You are not advised to drink alcohol while you are using Zyban tablets. Research has shown evidence of “adverse neuropsychiatric events” in people who consumed alcohol while being treated with Zyban. There is also evidence that suggests taking Zyban reduces alcohol tolerance, meaning you would become intoxicated quicker, or more than you would usually. Zyban and alcohol share some side effects, and drinking while taking Zyban may increase the risk of:
Whether you are taking Zyban to help you quit smoking, or as a treatment for depression or seasonal affective disorder, it is better to stay away from alcoholic drinks.
Zyban and Pregnancy
Zyban is not typically recommended for women who are pregnant. You would only be prescribed Zyban during pregnancy if your doctor concludes that the potential benefit outweighs the risk.
A study into birth outcomes following bupropion (Zyban) use during pregnancy, found that “while the risk of miscarriage following prenatal bupropion exposure was higher than that of a control group of women in one study, it remained within the general population rate”.
As the ingredients of Zyban may pass into breast milk, if you are breastfeeding you should inform your doctor before starting to use Zyban.
Zyban vs Champix
Like Zyban, Champix is a commonly prescribed medication for smoking cessation. However, the two drugs have different active ingredients and work in different ways. While Zyban, an antidepressant and smoking cessation aid, contains the active ingredient bupropion, Champix contains varenicline as its active ingredient. Champix is a nicotine agonist - by blocking nicotine receptors, Champix deactivates the reinforcement and reward system of nicotine use, meaning that you gain less pleasure from smoking.
While Zyban tablets come in 150 mg doses, Champix comes in 0.5 mg and 1 mg tablets. Zyban and Champix are both started one to two weeks before the smoking quit date.
If you are trying to quit smoking, the most effective treatment will be determined by your doctor. Both Zyban and Champix have been found to be more effective than placebo in reducing the urge to smoke.
Zyban vs Chantix
Zyban and Chantix (also available under the brand name Champix) are both medications that are prescribed for smoking cessation. But while Zyban contains the active ingredient bupropion, Chantix contains varenicline as its active ingredient. The two medications belong in different classes – while Zyban is an antidepressant and smoke cessation aid, Chantix is a nicotine agonist which works by deactivating the reinforcement and reward system to reduce the pleasure that you get from smoking.
Chantix tablets come in 0.5 mg and 1.0 mg strengths. Like Zyban, you would typically begin to take Chantix one to two weeks before your smoking quit date.
Many users of Zyban who had taken the drug for smoking cessation reported online that the medication had helped them to stop the habit. Reviewers online have said that Zyban initially helped them cut down, before eventually stopping smoking altogether. While some users were able to quit using 1x150 mg Zyban tablet per day, others found that they were only able to stop after their dosage was increased to 300 mg per day.
There are reports online of Zyban helping users to stop smoking in just a few days, while others said that it was a few weeks or months before they were able to stop smoking cigarettes entirely. Among the commonly-reported side effects are difficulty sleeping and a reduced appetite.
Can I Buy Zyban Over the Counter?
In the UK, you aren’t able to buy Zyban tablets over the counter. Before you can be issued a prescription for the medication, your suitability for the treatment will need to be assessed by a doctor. After your suitability for Zyban has been confirmed, you can use your electronic prescription to buy Zyban from a local or online pharmacy.
Why not buy Zyban at Cloud Pharmacy, benefitting from the convenience of our online service? Once you have completed a consultation with one of our online pharmacists, we can issue your prescription and dispense your Zyban tablets promptly. Your medication will then be dispatched in a discreet package with next-day delivery.
Zyban tablets come in 150 mg doses. As an adult who is trying to stop smoking, your dosage would typically be 150 mg of Zyban, once per day. Depending on the effectiveness of this dosage, your doctor may decide to increase it to 300 mg per day – this is 1x 150 mg tablet, taken twice per day.
You may need to take a lower dose of Zyban if you are at a higher risk of getting side effects. This may be applicable if you:
- Are aged over 65
- Are at a higher risk of fits
- Have liver disease
- Have kidney disease
How Long Does Zyban Take To Work?
You will begin taking Zyban tablets two weeks ahead of your ‘quit date’ while you are still smoking. This will give the medication time to build up in your body before you stop. When you do stop smoking, you should feel fewer withdrawal symptoms and cravings.
Most people will take Zyban for up to 12 weeks. The time it takes you to stop smoking, or whether you are successful in quitting the habit, will vary from person to person.
If you have been unsuccessful in stopping smoking 7 weeks after your quit date (9 weeks after starting to take Zyban), your doctor may advise you to cease taking the medication. In this case, you’ll stop taking Zyban gradually over a two-week period. You shouldn’t stop taking Zyban or change your dose unless advised to do so by your doctor. Stopping suddenly may cause withdrawal symptoms.
If you are struggling to give up, we recommend reading our helpful guide on how to quit smoking for more information.
How to Take Zyban
Zyban tablets should be taken once or twice per day, as prescribed by your doctor. If you are taking Zyban twice a day, leave at least 8 hours between each tablet. You shouldn’t take Zyban close to bedtime, as this might make it harder to sleep. Zyban tablets can be taken with or without food. Swallow the tablets whole with water, and never crush, split or chew them. If you take more Zyban tablets than you should, seek immediate medical help.
If you forget to take a dose of Zyban, wait until the usual time to take your next tablet. Don’t take two doses to make up for the dose you forgot.
Zyban Side Effects
One of Zyban’s most common potential side effects is sleeping difficulty, which can affect more than one in ten people - this is why you shouldn’t take Zyban close to bedtime. Other common potential side effects of Zyban, which can affect up to one in ten people, include:
- Difficulty concentrating
- Stomach pain
- Changes in taste
Uncommon side effects, which can affect up to one in 100 people, include:
- Increased blood pressure
- Ringing in the ears
- Affected sight
- Loss of appetite
- Rapid heartbeat
Severe side effects from Zyban are rare and affect up to one in 1,000 people. If you suffer any of the following:
- Uncontrolled movements
- Memory loss
- Severe skin rashes
- Patches of red skin
contact a medical professional or call 999 immediately.
Patient Information Leaflet
Zyban Tablets Patient Information Leaflet
For more information on Zyban medication, take a look at the patient Information Leaflet below:
Confirm Zyban Tablets treatment selection