Mebeverine 135mg Tablets

  • Mebeverine Tablets Online

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Fastest delivery available: 31/05/2024

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Pricing and quantity options

Alverine Citrate 60mg Capsules

Quantities 60mg
100 £17.99
200 £32.99

Mebeverine 135mg Tablets

Quantities 135mg
100 £10.98
200 £23.99
Registered UK Pharmacy number 9012073
Please note: This page is only to be used as a reference of our price for this medication. If you are approved you will be offered treatment for you and the prescriber to jointly consider. However, the final decision will always be the prescriber's.

Medication features

Mebeverine is a medicine that is used as an antispasmodic. As a result of this action, mebeverine reduces the movement of muscles in the digestive system and uterus, which reduces cramps. This can lead to the alleviation of symptoms that are common in patients who suffer from irritable bowel syndrome (IBS).

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  • Anti-spasmodic
  • Treatment of IBS
  • Relaxes muscles in the digestive system
  • Helps to reduce pain

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Buy Mebeverine Tablets Online

Mebeverine can be ordered from our UK registered online prescribing and next day delivery service. Simply complete an online medical questionnaire as part of your order. This helps our prescribers make sure it is safe and suitable to prescribe for you. 

If approved by our medical team, our pharmacy team will receive a prescription. This will be dispensed and dispatched to your delivery address. Our prices have bneem checked against our competitors and are amongst the cheapest online for all treatments. Please note that there are no hidden charges for prescriptions and delivery is free on orders over £35.

What is Mebeverine?

Mebeverine is a smooth muscle relaxant that is used for intestinal disorders like irritable bowel syndrome or IBS. Mebeverine, as an antispasmodic treatment, is effective at relaxing the muscles surrounding your intestine and uterus. Its use reduces stomach cramping, a common symptom of IBS.

What is Mebeverine used for?

Mebeverine is used to provide relief for irritable bowel syndrome and related intestinal disorders caused by spasms of the intestinal muscles, including chronic irritable colon, mucous colitis, spastic constipation, and spastic colitis.

How does Mebeverine work?

Mebeverine 135mg is a type of medicine called smooth muscle relaxant and is a treatment for the medical condition Irritable Bowel Syndrome (IBS). It is the active ingredient in the popular IBS medicine Colofac.

Smooth muscle is a muscle type that is not under voluntary control. It is the muscle that is found in places like the walls of the intestines and the womb. Mebeverine directly acts on this type of muscle, causing it to relax.

Mebeverine stops the muscle spasms occurring in the gut in conditions such as IBS and diverticular disease. This relieves the pain that is associated with these conditions.

What are the benefits of taking Mebeverine Tablets?

Mebeverine 135mg tablets are effective in reducing the most common symptom of IBS: stomach cramping. It effectively provides relief for irritable bowel syndrome and related intestinal disorders.

How do I take Mebeverine?

As with all medicines, please read the patient information leaflet before administering. 

For the relief of muscular pain, take ONE tablet of Mebeverine 135mg up to THREE times daily or as directed by your prescriber.

These must be taken by mouth with a glass of water, ideally 20 minutes before a meal.

Mebeverine Reviews

Mebeverine reviews are generally positive. Reviewers state that it has improved their stomach cramps with very few side effects. Many reviewers have said that the boost to their confidence and impact on their mental health has been really noticeable and that they highly recommend Mebeverine 135mg tablets.

Mebeverine Interactions

It's safe to take mebeverine with most prescription medicines, and everyday painkillers like paracetamol and ibuprofen.

However, it's generally best not to take it together with other IBS remedies, as these medicines work in the same way.

Do not take more than ONE IBS treatment at a time, unless a doctor advises otherwise. You're unlikely to get extra relief for your symptoms, and it may cause more side effects.

Mebeverine or Buscopan

Buscopan contains the active ingredient Hyoscine which works via a different mechanism to relieve muscle spasms in IBS. Mebeverine is different from Buscopan. 

Can you buy Mebeverine over the counter?

This medication can be purchased confidently from Cloud Pharmacy by selecting "start consultation" above. As an independent pharmacy, Cloud Pharmacy is able to get the best prices for both generic and brand name treatments. When compared to other retailers, Cloud Pharmacy can be as much as 50% cheaper to buy the same products.

Mebeverine in pregnancy

Speak to your doctor for advice if you are pregnant or planning on becoming pregnant before taking Mebeverine. In general, Mebeverine is not recommended for use during pregnancy or breast-feeding.

Mebeverine and Alcohol

Whilst it is possible to drink alcohol when taking Mebeverine, it is not recommended as alcohol can trigger IBS symptoms.

Mebeverine Summary

Ingredient Mebeverine
Mebeverine Dosage Take ONE tablet THREE times per day
Mechanism of Action The exact mechanism of action is not known. It is known it works on muscles in and around the gut to relieve symptoms of IBS.
How quickly does it work?Mebeverine starts to work after 1 hour. You should feel better 1 to 3 hours after taking it. 
Side Effects It is a relatively well-tolerated drug, and side effects are few. Should you experience any signs of an allergic reaction to Mebeverine however, seek medical help immediately. 

Side Effects
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Mebeverine Side Effects

Like with all medicine, Mebeverine Side Effects can occur but these aren’t experienced by everyone. If you experience any of these Mebeverine side effects, especially if any of them are getting progressively worse, immediately stop and speak to your doctor as soon as possible.

Below is a list of Mebeverine Side Effects experienced more, or less when people have taken Mebeverine 135mg tablets. For a full list, please refer to thepatient information leaflet.

The following are the common side effects of Mebeverine:

  • Skin irritation, dry mouth, bloating, heartburn
  • Allergic reactions mainly but not exclusively limited to the skin have been reported
  • Immune system disorders such as hypersensitivity
  • Skin and subcutaneous tissue disorders such as angioedema, urticaria, exanthema, and face oedema

If you have concerns about the safety of the product and its side effects, consult first with your doctor before you start using the medication.

If this is the first time that you experience IBS symptoms or symptoms of other intestinal disorders, talk first with your doctor before you start using Mebeverine.

Do not use Mebeverine without first consulting with your doctor if you have any of the following:

  • You are over 40 years old
  • You passed blood in your stool
  • You are feeling sick or being sick
  • You have lost your appetite or your weight
  • You look pale and feel tired
  • You are very constipated
  • You have fever
  • You have recently travelled abroad
  • You have abnormal vaginal bleeding or discharge
  • You have difficulty passing urine

Consult with your doctor if you get new symptoms, your symptoms get worse, or if your symptoms did not improve after 2 weeks of treatment.


Patient Information Leaflet
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Before taking any medication, it is important to read the Patient Information Leaflet. You can find information leaflets for your medicines by typing them into the search bar at, or by contacting us.

Can I buy Mebeverine online?
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Mebeverine can be purchased online from Cloud Pharmacy to treat IBS related symptoms that have been previously diagnosed and treated by your doctor. It is an antispasmodic medicine that can be requested via an online consultation with our prescriber who will ensure that this is the right treatment for you.

How long does Mebeverine take to work?

Mebeverine starts to work after one hour. You should feel better one to three hours after taking this treatment.

Ideally, you should take your Mebeverine tablet around 20 minutes before your main meals per day. This is because IBS sufferers normally find that their symptoms are strongest after they have eaten. Swallow the tablet or capsule whole with a drink of water; do not chew the tablet.

Taking a stronger Mebeverine dosage will not make Mebeverine work any faster and could be harmful to your health, causing negative side effects.



Mebeverine 135mg Tablets FAQs
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What is Mebeverine?

It is a medicine used to treat Irritable Bowel Syndrome (IBS). It is called an antispasmodic medicine because it relaxes the muscles in the digestive system.

It is an antispasmodic drug used to treat the symptoms of Irritable Bowel Syndrome (IBS). It is available on prescription and over the counter at certain pharmacies. The branded version is called Colofac. The active ingredient is mebeverine hydrochloride.

What are the side effects of Mebeverine?

Like all medicines, taking Mebeverine can cause some side effects. Some patients have reported dizziness or lightheadedness when taking this treatment. An allergic reaction is unlikely, but you may experience some redness, a rash, or itching. Seek medical help if the symptoms persist or get worse. Seek immediate medical help if you experience difficulties breathing or other severe allergic symptoms like the swelling of your face or tongue and hives.


Can Mebeverine help constipation?

The tablets help with stomach pain and cramps that are caused by muscle spasms. These are common symptoms of IBS but constipation is another common symptom. Unfortunately, Mebeverine does not treat constipation. Laxatives such as Fybogel can be used to treat constipation.

Is Mebeverine the same as Buscopan?

Buscopan is different from Mebeverine. Buscopan contains the active ingredient hyoscine which works differently, but can also help to relieve muscle spasms in IBS.

What does Mebeverine/Colofac do?

Mebeverine is an antispasmodic which means that it helps to relax the smooth muscle in the gut and control the cramps and painful stomach spasms associated with IBS.

Can I use Mebeverine while pregnant or breastfeeding?

There is little information regarding the use of Mebeverine during pregnancy. Speak to your GP before taking it. It is important to make your GP aware of any gastrointestinal symptoms during your pregnancy.

What is the standard dosage for Mebeverine?

The standard tablet dosage is 135mg, to be taken three times a day.

What is the best anti-spasmodic for IBS?

Each individual is different and have their own response. There are a few options including: Alverine, Colofac, Peppermint Oil, and Mebeverine. Speak to our team to determine which is best for you.

Is Mebeverine and Colofac available on the NHS?

Yes, Mebeverine is available on the NHS.

Mebeverine 135mg Tablets Reviews

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135mg 100 £10.98
135mg 200 £23.99