Vydura 75mg Tablets

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Fastest delivery available: 25/06/2024

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Pricing and quantity options

Zomig Tablets

Quantities 2.5mg
6 £39.99
12 £69.99

Zomig 5mg Nasal Spray (6 Pack)

Quantities 5mg
6 Sprays £59.99
12 Sprays £110.99

Zolmitriptan 2.5mg Tablets

Quantities 5mg (Orodispersible)
6 £27.99
12 £39.99
Quantities 2.5mg
6 £34.99
12 £49.99
Quantities 2.5mg (Orodispersible)
6 £35.99
12 £50.99
Quantities 5mg
6 £55.99
12 £93.89

Sumatriptan Tablets (50mg & 100mg)

Quantities 50mg
3 £5.89
6 £9.99
12 £18.99
18 £26.99
Quantities 100mg
6 £11.99
12 £20.99
18 £28.99

Rizatriptan 10mg Tablets

Quantities 10mg
3 £14.99
6 £19.99
9 £26.99
12 £34.99

Imigran Nasal Spray

Quantities 10mg
2 Sprays £38.99
Quantities 20mg
2 Sprays £39.99

Almotriptan 12.5mg Tablets

Quantities 12.5mg
3 £13.49
6 £19.99
9 £26.99
12 £34.99

Migraitan 50mg Tablets

Quantities 50mg

Vydura 75mg Tablets

Quantities 75mg
2 £49.99
4 £99.99
8 £149.99
16 £299.99
Registered UK Pharmacy number 9012073
Please note: This page is only to be used as a reference of our price for this medication. If you are approved you will be offered treatment for you and the prescriber to jointly consider. However, the final decision will always be the prescriber's.

Medication features

Vydura is a new migraine treatment approved in the UK to stop migraine attacks in both acute episodes or migraine prevention. It comes in an easy to administer wafer form (oral lyophilisate) where it dissolves on or below the tongue for quick absorption by the body.

It contains the active ingredient "Rimegepant" which is in a new class of migraine treatments called "gepants".


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  • Breakthrough migraine relief treatment
  • Fast acting wafer form
  • Free online consultation available
  • Next day delivery

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Buy Vydura tablets online for effective migraine relief 

Vydura (Rimegepant 75mg) can be ordered from our UK registered online prescribing service. Simply complete an online medical questionnaire as part of your order. This helps our prescribers make sure it is safe and suitable to prescribe for you. 

If approved by our medical team, our pharmacy team will receive a prescription. This will be dispensed and dispatched to your delivery address. 

What is Vydura and how does it work?

Vydura is a breakthrough migraine medication, that can effectively treat and relieve migraines in adults. The active ingredient is rimegepant which belongs to a new class of migraine medications called "Gepants". Vydura works by inhibiting the activity of calcitonin gene-related peptide (CGRP). CGRP is released by nerves and makes a migraine last longer. The active ingredient in Vydura, rimegepant, blocks the release of CGRP by attaching itself to the receptor for CGRP. This in turn helps to end migraines.

Triptans such as Sumatriptan & Rizatriptan lead to a tightening of blood vessels unlike Vydura. This means that the patient is less likely to experience side effects and the medication is suitable for people who have cardiovascular related co-morbidities. 

To learn more about migraines, look at our guide that answers the question ‘what is a migraine?’.

How effective is Vydura?

In clinical trials, it was shown to be highly effective when used for migraine relief:

  • In the first 24 hours, 86% of patients did not require any other interventions.
  • Between 2 and 48 hours, rimegepant provided 42% of patients with continued pain relief after the first dose.
  • 21% of patients were pain free within 2 hours.

Vydura (Rimegepant) 75mg Summary

Type of MedicineGepant
Active IngredientRimegepant
DoseUse one 75mg wafer daily for acute migraines and one 75mg wafer on alternate days for prevention

Mechanism of Action

Stops function of calcitonin gene-related peptide (CGRP) that makes the lengthens migraine episodes

Side Effects

Dizziness, Dry Mouth, Nausea
PriceFrom £49.99

Vydura migraine prescription medication alternatives

Whilst Vydura tablets are a new choice for migraine relief, it's beneficial to consider other medications, especially for individuals with unique health needs or preferences.

During your online consultation with a Cloud Pharmacy pharmacist, the following alternatives may be suggested:

  • Sumatriptan Tablets: Migraine medication, used to alleviate associated symptoms of headaches, nausea and light sensitivity. Take Sumatriptan migraine medication as soon as your migraine occurs in order to effectively tackle symptoms.
  • Zomig Tablets 2.5mg: Containing Zolmitriptan as its active component, this medication effectively treats migraines, whether they are preceded by an aura or not
  • Zolmitriptan Tablets: These tablets are effective in treating acute migraine headaches, although they do not prevent future episodes
  • Rizatriptan Tablets: Useful for alleviating migraines and their accompanying symptoms, such as nausea, pain, and visual disturbances. For more information, take a look at our guide that compares Rizatriptan and Sumatriptan
  • Almotriptan Tablets: These tablets aid in reducing migraine-related headaches, light sensitivity, and nausea by narrowing the blood vessels in the brain.

Vydura Over The Counter Alternatives

Below we’ve compiled a list of over-the-counter (OTC) alternatives to Vydura tablets. Please consult a healthcare professional if you are considering taking any of these with Vydura 75mg tablets.

  • Paracetamol: Common for various pains, including headaches. For migraines, take two tablets every four hours, not exceeding four doses in 24 hours
  • Ibuprofen: Effective for mild to moderate pain, including migraines. Can be combined with paracetamol for better symptom management
  • Anadin Extra: Combination of aspirin, paracetamol, and caffeine. Take two tablets up to four times a day, with a 24-hour limit of eight tablets
  • Solpadeine Plus: Contains paracetamol, codeine, and caffeine. Suitable for those who have difficulty swallowing pills. Limit use to three consecutive days due to addiction risk
  • Migraleve: Specialized for migraines, with paracetamol, codeine, and buclizine. Use Migraleve Pink at migraine onset and Migraleve Yellow four hours later if needed. Maximum eight tablets in 24 hours and three consecutive days of use

Informational sources

If you’d like to find out more about Vydura tablets or migraines in general, we’ve compiled a list of additional resources below for you to take a look at:

Side Effects
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Vydura side effects

Vydura has some common and less common side effects. Most people experience no side effects or minor issues.

Common side effects of Vydura

  • Nausea or vomiting
  • Dizziness
  • Dry mouth

These can also be associated with migraines and cluster headaches, so you might not even notice them as side effects. However, consult your doctor or pharmacist if they are severe or last longer than a few days.

Provided these side effects aren’t severe, it is usually safe to wait a few days and see if they subside. If you are concerned, speak to your doctor.

Serious side effects of Vydura

Serious side effects are rare. However, if you experience the following, seek medical attention immediately:

  • Tingling or tightness in your chest
  • Tingling or tightness elsewhere on your body, including your arms, legs, or face
  • Heaviness in your body
  • Warmth or cold in your face

If any of these symptoms feel very intense, seek emergency medical care.

Rarely do people experience a severe allergic reaction to this medication. However, it’s important to know what to look out for. Severe allergic reaction symptoms include:

  • Wheezing or spluttering
  • Trouble breathing or talking
  • Swelling in the tongue, face, throat, and lips
  • Severe tightness in the chest or throat

If you experience this, go to A&E immediately or call 999.

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Vydura warnings

Inform your doctor in case the following applies to you:

  • have severe liver problems
  • have reduced kidney function or dialysis
  • are under 18
  • are pregnant, breastfeeding or planning to get pregnant

Additonally, inform your doctor of all the medications you are currently taking, both prescription and over-the-counter, as these could interact with this medication:

  • Itraconazole and clarithromycin to treat fungal or bacterial infections
  • Ritonavir and efavirenz to treat HIV infection
  • St. John’s wort to treat depression
  • Bosentan to treat high blood pressure
  • Phenobarbital to treat epilepsy
  • Rifampicin to treat tuberculosis
  • Modafinil to treat narcolepsy

Doctors recommend that you do not take Vydura more than once every 48 hours if you are taking:

  • Fluconazole and erythromycin to treat fungal or bacterial infections
  • Diltiazem, quinidine, and verapamil to treat an abnormal heart rhythm, chest pain (angina) or high blood pressure
  • Cyclosporin to prevent organ rejection after an organ transplant


Patient Information Leaflet
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Before taking any medication, it is important to read the Patient Information Leaflet. 

These can be found on medicines.org by typing them into the search bar.

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Vydura dosage & directions of use

For acute migraine attacks, let one 75mg wafer dissolve below the tongue without consuming alongside food or fluids. If required, you can take another Vydura dose 24 hours after the first dose as you should never take more than one Vydura wafer in a 24 hour period.

For the prevention of migraines, you can take one 75mg wafer on alternate days.

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Vydura Ingredients

Ingredients that make up Sumatriptan tablets include:

  • Active Component: Rimegepant sulfate

Additional Ingredients include:

  • Gelatin
  • Mannitol (E421)
  • Mint flabour
  • Sucralose

Always check with a healthcare professional before taking Vydura to ensure you are not allergic to any ingredients.

Vydura 75mg Tablets FAQs
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What is A Migraine?

Migraines generally start as a dull ache and then develop into a throbbing and pulsating constant pain that you will likely feel at the temples as well as the front or back of both sides of your head. The pain usually comes with bouts of nausea, vomiting and hypersensitivity to light and sound. Prior to a migraine attack, some people will experience something called an aura (about 25% of people who suffer from migraines).

What Causes Migraines?

The cause of mingraines is stilll somewhat ambiguous however it is believed to be caused by a chemical reaction in the brain which leads to constriction of certain vessels, triggering the headache. There is thought to be both environmental and genetic factors which influence who gets migraine as well as susceptibility to migraine attacks.

How Do I Treat Migraines?

Migraines can be treated using a variety of techniques, however unfortunately, there is no cure for migraines. The most common way to deal with migraines is to use a particular class of medcations known as triptans. Triptans are used to treat the acute migraine symptoms. However there are some prophylactic/preventative treatments that can be take for the treatment of migraine such as propranolo and topiramate.

What is A Migraine Aura?

Around 20-25% of people who suffer from Migraine will likely have an aura prior to the migraine itself. An aura can be described as varying intensities of certain neurological symptoms that act as a 'warning sign' to tell you that you are about to have a migraine. An aura can manifest as you seeing wavy or jagged lines, dots or flashing lights- this often described as a chemical or electrical wave that moves accross the visual cortex. Auras can also lead to you having tunnel vision or blind spots in one or both eyes. There are other symptoms associated with a migraine aura such as auditory/visual hallucinations, changes in small (phantom smells), numbness, pins and needles or speech disturbances. 

Can The Weather Affect Migraines?

For some people, weather changes can cause an imbalance in neurotransmitters and chmicals in the brain such a sereotning (5-HT), which can lead to more frequent migraines. Bright sunshine as well as hot and humid conditions may lead to your migraines being triggered. Some studies have shown that low barometric pressure can act as a trigger for migraines for some people.

What is A Migraine Trigger?

Migraine triggers vary person to person; something that affects one person may not affect the other. Surveys, diary studies and clinical trials have inidicated that stress, menstrual cycle changes, weather changes, sleep disturbances, alcohol, and other foods are among the most common factors mentioned when it comes to triggering a migraine. To help prevent migraines it is important to keep a diary of when you have a migraine attack. This allows for you to pin-point what may be causing your migraine and therefore drastically reducing your chance of getting a migraine.

Am I More Likely to Get A Stroke if I Suffer From Migraine?

Migraines are generally considered a relatively benign neurological condition. However, research has shown an association between migraines and stroke, and especially between migraine with aura and ischaemic stroke. Patients can also suffer from migrainous infarction (blood clot), a subset of ischaemic stroke that often occurs in the posterior circulation of younger women. The exact origina of migrainous associated infarction is not known, but it is theorised that the duration and local neuronal energy level from cortical spreading depression may be a prime factor.

Is There A Link Between Hormonal Changes and Migraine?

Horomones are proteins that are responsible for the regulation and overall biochemical function of our body to allow for complete balance and homeostasis as your environment changes. If you have a hormonal imbalance in your body during menopause, pregnancy or mestruation it can lead to a migraine attack

What Medications Can Be Used to Treat The Acute Symptoms of Migraine?

Acute medications are used to treat the pain of the headache after the migraine has started. Examples of acute migraine medications are some NSAIDS (ibuprofen/diclofenac/naproxen), ergots (ergotamine) and triptans (sumatriptan/rizrtriptan/zolmitriptan)

How Can I learn More About Migraines?

There are a variety of resources available to learn about migraines online. We have summarised the most reliable sources on our cloud pharmacy blog: Migraines: More Than Just A Headache

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